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BioPro Series

BioPro and BioPro SmartSep, ion exchange media with high dynamic binding capacities and high recoveries, are suitable for downstream chromatographic purification processes in biopharmaceutical manufacturing. BioPro and BioPro SmartSep are suitable for initial purification(capture) and for intermediate to final purification(polishing), respectively.
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BioPro Series

BioPro and BioPro SmartSep, ion exchange media with high dynamic binding capacities and high recoveries, are suitable for downstream chromatographic purification processes in biopharmaceutical manufacturing. BioPro and BioPro SmartSep are suitable for initial purification(capture) and for intermediate to final purification(polishing), respectively.

YMC-BioPro, ion exchange columns with high resolution, are suitable for uniformity tests, such as isoform analysis in quality control and characterization of biopharmaceuticals.

Media

BioPro Ion Exchange Media

BioPro SmartSep

BioPro Q

BioPro S

BioPro DA

BioPro CM

BioPro SmartSep Q

BioPro SmartSep S

Matrix

Hydrophilic porous polymer

Particle size(μm)

75

60

10, 20, 30

Ion exchanger

-R-N+(CH3)3

-R-SO3-

-R-N(CH3)2

-R-COOH

-R-N+(CH3)3

-R-SO3-

Feature

Suitable for capture and intermediate purification step

High binding capacity

Suitable for intermediate purification step and polishing step

High-throughput purification by utilizing mechanical strength

polymer beads

BioPro Ion Exchange Screening Kit

Available in four chemistries: Strong ion exchangers and weak ion exchangers

For media screening, develop of purification method and loadability study

Column

YMC-BioPro(packed column)

YMC-BioPro QA-F

YMC-BioPro SP-F

YMC-BioPro QA

YMC-BioPro SP

Matrix

Hydrophilic non-porous polymer

Hydrophilic porous polymer

Particle size(μm)

3, 5

5

Ion exchanger

-CH2N+(CH3)3

-CH2CH2CH2SO3-

-CH2N+(CH3)3

-CH2CH2CH2SO3-

Feature

For increasing resolution and throughput

High efficiency with low operating pressure

Suitable for characterization of biopharmaceuticals and quality control

Suitable for laboratory-scale purification

High binding capacity and high recovery of biomolecules

Products subjected to purification process of biopharmaceuticals

Process

Required media performance

BioPro products

Capture

High binding capacity in high flow rate

Excellent characteristic of pressure and flow rate realizing high flow rate

BioPro(75, 60 μm)

Intermediate

High resolution to remove most of impurity

High binding capacity

Easy to scale up

Excellent mechanical strength and pressure resistance

BioPro SmartSep
(10, 20, 30 μm)

Polishing

Quite high performance to separate impurities whose retention time close to each other

Low nonspecific binding capacity

Analytical

High resolution and excellent lot-to-lot reproducibility

YMC-BioPro(packed column)

We could not find any corresponding parameters, please add them to the properties table
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